Tesamorelin: Visceral Fat’s Worst Enemy

What is Tesamorelin?

Tesamorelin is a synthetic peptide that stimulates the release of growth hormone by acting on the pituitary gland. Unlike other peptides, Tesamorelin is FDA approved for use and is commonly used to treat conditions related to growth hormone deficiencies, particularly in people with HIV-associated lipodystrophy, a condition that causes abnormal fat accumulation. This adnormal fat accumulation occurs around the organs as visceral fat.

What does Tesamorelin do? 

Tesamorelin offers a variety of benefits, particularly for those looking to address issues related to fat accumulation and body composition. The key benefits include:

• Reduction in visceral fat, particularly in the abdominal area.
• Improvement in overall body composition by promoting fat loss and increasing lean muscle mass.
• Improvement in cognitive function and mood by optimizing growth hormone levels.
• Potential to improve skin elasticity, which may lead to reduced signs of aging.
• Increased energy levels and enhanced athletic performance due to better metabolic function.
• Reduces the levels of cholesterol and triglycerides by carrying out the process of lipolysis.
• Reduces the progression of carotid atherosclerotic vascular disease.

These benefits make Tesamorelin particularly attractive to individuals looking to enhance their physique, combat the effects of aging, or improve metabolic health. By stimulating the release of growth hormone, Tesamorelin accelerates the body’s fat-burning processes and can lead to significant reductions in fat percentage. However, its effectiveness in weight loss is often most pronounced when combined with a healthy diet and regular exercise. It also promotes muscle proliferation through satellite cells, decreases muscle breakdown, and also prevents toxin-induced inflammation of muscles.

Dosage of Tesamorelin:

A good starting dosage of Tesamorelin would be 1MG a day for the first week or two to gauge reaction to the peptide. You would either follow a 5 on 2 off or 6 on 1 day off from taking the peptide. After one or two weeks, the typical dosage of Tesamorelin would increase to 2 mg per day and stay at the dosage continuing forward for eight to twelve weeks followed by a break of the same amount of time. The dosage can vary depending on the specific needs and goals of the user.

Side Effects of Tesamorelin:

As with any medication or supplement, Tesamorelin may cause side effects, though they are generally mild.

Common side effects include:

• Injection site reactions such as pain, redness, or swelling.
• Headaches or dizziness.
• Joint pain or muscle discomfort.
• Flushing or feeling warm in the face.
• Increased blood sugar levels in some individuals.

Serious side effects are rare but may include allergic reactions, which would require immediate medical attention. 

One scientific study concluding the effectiveness of Tesamorelin can be found:

HERE

Tesamorelin Stacking:

Considering the more or less similar mechanism of action and the benefits, Tesamorelin appears that it can be stacked with the Ipamorelin peptide to achieve an optimum growth hormone (GH) release. Some studies suggest taking Ipamorelin in the morning while fasted and Tesamorelin at night before bed.